The IGF and IGFBP System in Insulin Resistance and Diabetes Mellitus

作者: Kerstin Brismar , Moira S. Lewitt

DOI: 10.1007/978-1-59259-795-6_14

关键词: EndocrinologyGlucose homeostasisInternal medicineDiabetes mellitusMedicineBeta cellInsulin resistanceDisease riskInsulin

摘要: The IGF system and insulin play complementary roles in the maintenance of glucose homeostasis. The IGFs are important beta cell survival factors. IGFBP-1 is a marker hepatic action. Low levels IGFBP-1 associated with resistance cardiovascular disease risk. High indicate need for increased replacement diabetes.

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