Immunohistochemical evidence for the heterogeneity of maternal and fetal vascular endothelial cells in human full-term placenta
作者： Ingrid Lang , Michaele Hartmann , Astrid Blaschitz , Gottfried Dohr , Gerhard Skofitsch
DOI: 10.1007/BF00318740
关键词: Endothelial stem cell 、 Immunology 、 Monoclonal antibody 、 Fetal membrane 、 Antigen 、 Placenta 、 Biology 、 Pathology 、 Immunohistochemistry 、 Antibody 、 Endothelium
摘要: The heterogeneity of endothelial cell surface antigen expression was studied in 5 human full-term placentae by means indirect immunohistochemistry using 9 monoclonal antibodies and staining with fluorescent-conjugated Ulex europaeus lectin, both which are widely used markers. (1) A highly specific, homogeneous fetal maternal placental vessels all sizes anatomical regions observed the PAL-E, QBEND10 1F10. These were even more specific than factor VIII antibody von Willebrand antibody, cross-reacted some non-endothelial cells structures. reactivity 1F10 residual basal plate strongly suggests an origin these cells. (2) In contrast to other organs, HM 15/3 stained macrovascular system placenta. This might indicate organ-associated (3) Monoclonal against receptors for transferrin IgG (FcγRII) labeled increasing intensity distal insertion umbilical cord. cord itself unreactive. suggest a macro- microvascular
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