Parkinson's disease-related perfusion and glucose metabolic brain patterns identified with PCASL-MRI and FDG-PET imaging.

作者: Laura K. Teune , Remco J. Renken , Bauke M. de Jong , Antoon T. Willemsen , Matthias J. van Osch

DOI: 10.1016/J.NICL.2014.06.007

关键词: Magnetic resonance imagingCerebral metabolic ratePerfusion scanningMedicineNetwork activityArterial spin labelingParkinson's diseaseCerebral blood flowPerfusionNuclear medicine

摘要: Introduction Under normal conditions, the spatial distribution of resting cerebral blood flow and metabolic rate glucose are closely related. A relatively new magnetic resonance (MR) technique, pseudo-continuous arterial spin labeling (PCASL), can be used to measure regional brain perfusion. We identified a Parkinson's disease (PD)-related perfusion covariance pattern in same patients using PCASL FDG-PET imaging assessed (dis)similarities disease-related between metabolism PD patients.

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