Zwitterionic pyridinecarboxylic acids
作者： Bego�a Garc�a , Saturnino Ibeas , Jos� M. Leal
DOI: 10.1002/(SICI)1099-1395(199609)9:9<593::AID-POC593>3.0.CO;2-7
关键词: Protonation 、 Chemistry 、 Potentiometric titration 、 Isonicotinic acid 、 Picolinic acid 、 Zwitterion 、 Nuclear chemistry 、 Cationic polymerization 、 Organic chemistry
摘要: A study of the acid-base behaviour three isomeric pyridinecarboxylic acids (picolinic, nicotinic and isonicotinic acid) was carried out using spectrophotometric potentiometric measurements. The cationic form picolinic acid converts partially into corresponding zwitterion (pK1) within a borderline acidity range where neither pH scale nor functions work satisfactorily. Protonation carboxyl groups (pK33) occurred at highest levels employed. medium effects observed on spectral curves were corrected by factor analysis. measurements gave values for pK1 pK2 only, which in good agreement with those determined spectrophotometrically.
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