TUBULO-GLOMERULAR FEEDBACK

作者: Klaus Thurau

DOI: 10.1016/B978-0-08-026824-8.50010-2

关键词: Gap junctionSyncytiumKidneyMembraneReabsorptionEndocrinologyBiophysicsInternal medicineInterstitial volumeJuxtaglomerular apparatusFiltrationChemistry

摘要: Publisher Summary Filtration of fluid through capillary membranes into the interstitium and reabsorption filtrate blood is a common place in all beds circulation proceeds by what referred to as Starling mechanism. Only when these two processes are balance with each other, steady state interstitial volume exists. This chapter explains that for main circulation, between filtration must exist kidney, which known tubulo-glomerular balance. The theory feedback system structurally bound juxtaglomerular apparatus (JGA). plays an important role adjustment rate reabsorptive capacity tubular epithelium proximal tubule Henle loop. Both epithelial cells lacis together mesangial located center glomerular tuft interconnected tight gap junctions suggests functional syncytium formed cellular elements JGA.

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