Risk factors for the prevalence of nevi: a review

摘要: Melanoma is becoming an important public health problem as incidence rates in many white populations continue to increase. Numerous studies have identified potential risk factors for melanoma [1]. The association of early childhood sun exposures with supports the importance ultraviolet exposure development [2–6]. Nevi, commonly known moles, may be precursors melanoma. evidence this based on two types studies. First, clinical and pathologic suggests that nevi are [7]. Patients often report their developed at site a pre-existing nevus [8,9]. Observation remnants dysplastic other histologically melanomas support patient observation [9–13]. Second, epidemiologic shown number strong indicator developing [4,14–21]. This finding seems consistent throughout literature regardless method defining (i.e. by type, size, or location) [22]. Dubin et al. [16] used total body charts self-assessment distribution, relative 2.0 26–100 compared less than 25 3.4 more 100 nevi. Swerdlow [21] found risks no 4.4 10–24 nevi, 8.7 25–49 63.8 50 over whole body. Similarly they 1.7 1–9 arms 10.2 10 [21]. increasing numbers either markers some leads melanoma, both [10].