Somatic Growth in Children With Single Ventricle Physiology: Impact of Physiologic State

作者: Kelly N. Vogt , Cedric Manlhiot , Glen Van Arsdell , Jennifer L. Russell , Seema Mital

DOI: 10.1016/J.JACC.2007.07.050

关键词: MedicinePopulationSurgeryVolume overloadHypoxemiaInternal medicineVentricleFontan procedureBirth weightRepeated measures designCardiologyHemodynamics

摘要: Objectives We sought to define somatic growth patterns for patients with single ventricle (SV) physiology and associated factors. Background Infants SV might have retardation volume overload hypoxemia, which improve after surgical palliation. Methods reviewed 126 (35% male) who underwent the Fontan procedure from 1994 2004. Demographic data, hemodynamic variables, procedures were recorded. Serial weights heights converted z-scores. Linear regression analysis adjusted repeated measures was used model trends. Results Median z-score weight −0.7 at birth, −1.6 before bidirectional cavopulmonary shunt (BCPS), procedure, procedure. A significant decline in z-scores seen BCPS, reversed hemi-Fontan stabilized The BCPS lower birth (p Conclusions show impaired BCPS. Although catch-up occurs effective interventions such as more intensive nutritional strategies be targeted this high-risk population. presence of systemic venous collaterals impede secondary impairment. Embolization allow maximum potential.

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