Novel Microbubbles for Ultrasonic Imaging Based on Surfactants

摘要: In this study, Span 60 (sorbitan monostearate) and PEG40S (polyoxyethylene 40 stearate) are employed to generate stabilized microbubbles for use in diagnostic ultrasound. The particle size analysis of the surfactant-coated showed that they appropriately sized intravenous administration. dependence on composition π-A isotherms mixed monolayers can be considered as evidence miscibility, though not necessarily homogeneous, indicating presence mutual interactions between two components. To obtain a kind novel bi-mode agents with both ultrasound fluorescent imaging properties, we combined CdTe quantum dots (QDs) together via layer by assembly (LBL) technique. Through spectra confocal laser scanning microscopy, it was confirmed nanoparticles were successfully deposited outer surface microbubbles. These exhibit high degree echogenicity under B-mode scan, regular Doppler color Doppler. They useful contrast provide better resolution ultrasonic diagnostics, including echocardiography.