Cognitive Inflexibility in Gamblers is Primarily Present in Reward-Related Decision Making.

摘要: One hallmark of gambling disorder is the observation that gamblers have problems stopping their behavior once it initiated. On a neuropsychological level has been hypothesized this result cognitive inflexibility. The present study investigated inflexibility in patients with using task involving reward element (i.e., reversal learning) and measuring general without such component response perseveration). For purpose, scores reward-based learning (Probabilistic Reversal Learning Task) Wisconsin Card Sorting Task were compared between group treatment seeking gender age matched control group. results show pathological impaired performance on neurocognitive based However, no difference groups observed regarding non-reward This suggests an aberrant learning, not more problem flexibility. pattern suggestive dysfunction orbitofrontal cortex, ventrolateral prefrontal cortex ventral regions striatum gamblers. Relevance for neurocognition problematic discussed.