Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
作者： Zhenyu Cai , Siriporn Jitkaew , Jie Zhao , Hsueh-Cheng Chiang , Swati Choksi
DOI: 10.1038/NCB2883
关键词: RIPK1 、 Programmed cell death 、 Cell membrane 、 Jurkat cells 、 Necroptosis 、 TRPM7 、 Phosphorylation 、 Cell biology 、 Biology 、 Transport protein
摘要: The mixed lineage kinase domain-like protein (MLKL) has recently been identified as a key RIP3 (receptor interacting protein 3) downstream component of tumour necrosis factor (TNF)-…
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