Inosine Triphosphate Protects Against Ribavirin-Induced Adenosine Triphosphate Loss by Adenylosuccinate Synthase Function
作者： Yuki Hitomi , Elizabeth T. Cirulli , Jacques Fellay , John G. McHutchison , Alexander J. Thompson
DOI: 10.1053/J.GASTRO.2010.12.038
关键词: Adenosine triphosphate 、 ITPA 、 Inosine monophosphate 、 Molecular biology 、 Adenylosuccinate synthase 、 ATPase 、 Adenosine 、 Adenosine monophosphate 、 Biology 、 Guanosine triphosphate 、 Pharmacology
摘要: Background & Aims Genetic variation of inosine triphosphatase (ITPA) causing an accumulation of inosine triphosphate (ITP) has been shown to protect patients against ribavirin (RBV)-…
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