Percentage of glycosylated serum ferritin remains low throughout the course of adult onset Still's disease
作者： Stéphane Vignes , Gisèle Le Moël , Bruno Fautrel , Bertrand Wechsler , Pierre Godeau
DOI: 10.1136/ARD.59.5.347
关键词: Medicine 、 Internal medicine 、 Still Disease 、 Pathology 、 Age of onset 、 Gastroenterology 、 Ferritin 、 Serum ferritin 、 Connective tissue disease 、 Rheumatoid arthritis 、 Adult-onset Still's disease 、 Retrospective cohort study
摘要: OBJECTIVE—To determine the evolution of levels total serum ferritin and percentage glycosylated form in patients with adult onset Still's disease (AOSD) at time diagnosis during follow up. METHODS—All AOSD were tested up. Total analysed by immunoassay, was determined methods using Sepharose-Con A. RESULTS—14 (eight women, six men) enrolled. At diagnosis, mean (SD) age 36 (16) years. Mean initial 6350 (1300) µg/l (normal 50%). up 37 (35) months. last examination all remission except one, who presented a chronic articular form. remained high this single patient normal 13 others, 98 (73) µg/l. In low, 16 (16)%. CONCLUSION—Total is marker active phase AOSD. The low both remission. Further studies are needed to confirm these data their specificity for before considering any possible use as diagnostic tool suspected AOSD, especially when atypical or previously treated.
sci-hub.se 参考文章(14)
M. Dueymes, P. Youinou, N.-G. Mimassi, Y. L. Pennec, V. Devauchelle, C. Basset, Changes in glycosylation of immunoglobulins in primary Sjögren's syndrome. Annales De Medecine Interne. ,vol. 149, pp. 42- 44 ,(1998)
T Nagayoshi, M Yamaguchi, M Hiida, H Kaneoka, A Ohta, Adult Still's disease: review of 228 cases from the literature. The Journal of Rheumatology. ,vol. 14, pp. 1139- 1146 ,(1987)
S. J. Cragg, M. Wagstaff, M. Worwood, Sialic acid and the microheterogeneity of human serum ferritin. Clinical Science. ,vol. 58, pp. 259- 262 ,(1980) , 10.1042/CS0580259
Gilbert Ashwell, Anatol G. Morell, The Role of Surface Carbohydrates in the Hepatic Recognition and Transport of Circulating Glycoproteins Advances in Enzymology - and Related Areas of Molecular Biology. ,vol. 41, pp. 99- 128 ,(2006) , 10.1002/9780470122860.CH3
J W Drysdale, P Arosio, T G Adelman, On ferritin heterogeneity. Further evidence for heteropolymers. Journal of Biological Chemistry. ,vol. 253, pp. 4451- 4458 ,(1978) , 10.1016/S0021-9258(17)34741-5
Toshiyuki Ota, Shuichi Higashi, Hidero Suzuki, Sumiya Eto, Increased serum ferritin levels in adult Still's disease. The Lancet. ,vol. 329, pp. 562- 563 ,(1987) , 10.1016/S0140-6736(87)90204-2
Henri DEBRAY, Dominique DECOUT, Gérard STRECKER, Geneviève SPIK, Jean MONTREUIL, Specificity of Twelve Lectins Towards Oligosaccharides and Glycopeptides Related to N‐Glycosylproteins FEBS Journal. ,vol. 117, pp. 41- 51 ,(2005) , 10.1111/J.1432-1033.1981.TB06300.X
S. Higashi, T. Ota, S. Eto, Biochemical analysis of ferritin subunits in sera from adult Still's disease patients Rheumatology International. ,vol. 15, pp. 45- 50 ,(1995) , 10.1007/BF00262707
M Schwarz-Eywill, B Heilig, H Bauer, A Breitbart, A Pezzutto, Evaluation of serum ferritin as a marker for adult Still's disease activity. Annals of the Rheumatic Diseases. ,vol. 51, pp. 683- 685 ,(1992) , 10.1136/ARD.51.5.683
Mario Cazzola, Caterina Borgna-Pignatti, Piero de Stefano, Gaetano Bergamaschi, Ilde G. Bongo, Laura Dezza, Franco Avato, Internal distribution of excess iron and sources of serum ferritin in patients with thalassemia. Scandinavian Journal of Haematology. ,vol. 30, pp. 289- 296 ,(2009) , 10.1111/J.1600-0609.1983.TB01494.X