Detection and Management of Early Gastric Cancer.

作者: Kentaro Sugano

DOI: 10.1007/S11938-015-0070-Y

关键词: SubmucosaMedicineHelicobacter pyloriEarly Gastric CancerEndoscopic resectionSurgeryResectionEsophagusEndoscopic mucosal resectionLymphatic system

摘要: Early gastric cancer (EGC), defined as being confined to the submucosa, is a curable condition. In recent years, endoscopic mucosal resection (EMR) and submucosal dissection (ESD) have been widely applied subgroups of cancers, thereby avoiding burden operation while preserving function. However, it can be difficult identify which often evade detection due their flat shapes without ulceration. Proper preparation clean surface, detailed systematic observation entire stomach, use high-resolution systems for both endoscopies equipped with image-enhanced modality monitors would facilitate such lesions. It also critical evaluate resected specimen confirm completeness (tumor-free lateral vertical margins well absence lymphatic vascular invasion). If incomplete, further treatment usually recommended—further patients positive or surgery involvement. The five-year survival endoscopically EGC excellent—and comparable that surgical therapy. Since most cancers are caused by Helicobacter pylori, this infection should tested routinely. patient H. pylori-positive, eradication recommended, heterotopic, metachronous recurrence subsequently reduced. Importantly, basic principles early diagnosis neoplasms arising in other parts gut, esophagus colon, beneficial through organ function minimizing operative intervention.

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