Impact of endoscopic suturing of the gastroesophageal junction on lower esophageal sphincter function and gastroesophageal reflux in patients with reflux disease.
作者： William C E Tam , Richard H Holloway , John Dent , Rachael Rigda , Mark N Schoeman
DOI: 10.1111/J.1572-0241.2004.04035.X
关键词: Endoscopy 、 Esophageal sphincter 、 Surgery 、 Gastroesophageal Junction 、 Esophageal disease 、 Disease 、 Heartburn 、 Medicine 、 Gastroenterology 、 GERD 、 Internal medicine 、 Reflux
摘要: Objectives Plication of the gastroesophageal junction by endoscopic suturing has been reported to improve symptoms and reduce acid exposure in patients with reflux disease (GERD). The mechanisms underlying these effects are not well defined. aims our study were determine impact on lower esophageal sphincter (LES) function GERD. Methods In 15 (7 males) GERD (heartburn, % time pH Results Six months after treatment, rate transient LES relaxations (tLESRs) was decreased 37% (p Conclusions GERD, results a reduction tLESRs, an increase basal pressure. These changes result only modest reflux.
core.ac.uk
nature.com
sci-hub.se 参考文章(27)
S. J. Franzi, C. J. Martin, M. R. Cox, J. Dent, Response of canine lower esophageal sphincter to gastric distension. American Journal of Physiology-gastrointestinal and Liver Physiology. ,vol. 259, ,(1990) , 10.1152/AJPGI.1990.259.3.G380
P.J. Kahrilas, W.J. Dodds, W.J. Hogan, M. Kern, R.C. Arndorfer, A. Reece, Esophageal Peristaltic Dysfunction in Peptic Esophagitis Gastroenterology. ,vol. 91, pp. 897- 904 ,(1986) , 10.1016/0016-5085(86)90692-X
Ravinder K. Mittal, Richard W. McCallum, Characteristics and Frequency of Transient Relaxations of the Lower Esophageal Sphincter in Patients With Reflux Esophagitis Gastroenterology. ,vol. 95, pp. 593- 599 ,(1988) , 10.1016/S0016-5085(88)80003-9
Z Mahmood, BP McMahon, Q Arfin, PJ Byrne, JV Reynolds, EM Murphy, DG Weir, Endocinch therapy for gastro-oesophageal reflux disease: a one year prospective follow up Gut. ,vol. 52, pp. 34- 39 ,(2003) , 10.1136/GUT.52.1.34
V Velanovich, Comparison of generic (SF-36) vs. disease-specific (GERD-HRQL) quality-of-life scales for gastroesophageal reflux disease. Journal of Gastrointestinal Surgery. ,vol. 2, pp. 141- 145 ,(1998) , 10.1016/S1091-255X(98)80004-8
Ravinder K. Mittal, Richard H. Holloway, Roberto Penagini, L. Ashley Blackshaw, John Dent, Transient lower esophageal sphincter relaxation Gastroenterology. ,vol. 109, pp. 601- 610 ,(1995) , 10.1016/0016-5085(95)90351-8
Mounes Dakkak, John R. Bennett, A New Dysphagia Score With Objective Validation Journal of Clinical Gastroenterology. ,vol. 14, pp. 99- 100 ,(1992) , 10.1097/00004836-199203000-00004
Sritharan S. Kadirkamanathan, David F. Evans, Feng Gong, Etsuro Yazaki, Mark Scott, C.Paul Swain, Antireflux operations at flexible endoscopy using endoluminal stitching techniques: an experimental study Gastrointestinal Endoscopy. ,vol. 44, pp. 133- 143 ,(1996) , 10.1016/S0016-5107(96)70130-X
William C.E. Tam, Mark N. Schoeman, Qing Zhang, John Dent, David S. Utley, Rachael Rigda, Richard H. Holloway, Delivery of radiofrequency energy (RFe) to the lower esophageal sphincter (LES) and gastric cardia inhibits transient LES relaxations and gastroesophageal reflux in patients with reflux disease Gastroenterology. ,vol. 120, ,(2001) , 10.1016/S0016-5085(08)80079-0
Charles J. Filipi, Glen A. Lehman, Richard I. Rothstein, Isaac Raijman, Gregory V. Stiegmann, J.Patrick Waring, John G. Hunter, Christopher J. Gostout, Steven A. Edmundowicz, Donal P. Dunne, Patrice A. Watson, Douglas A. Cornet, Transoral, flexible endoscopic suturing for treatment of GERD: a multicenter trial. Gastrointestinal Endoscopy. ,vol. 53, pp. 416- 422 ,(2001) , 10.1067/MGE.2001.113502