Intracellular Activation of Bioorthogonal Nanozymes through Endosomal Proteolysis of the Protein Corona.

作者: Xianzhi Zhang , Yuanchang Liu , Sanjana Gopalakrishnan , Laura Castellanos-Garcia , Gengtan Li

DOI: 10.1021/ACSNANO.0C00629

关键词: Bioorthogonal chemistryProtein CoronaIntracellularEndosomeStimulus responseProdrugBiophysicsProteolysisChemistry

摘要: Bioorthogonal activation of prodrugs provides a strategy for on-demand on-site production therapeutics. Intracellular to localize therapeutics, potentially minimiz...

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