作者: Marie-France Hurteau
DOI:
关键词: Anatomy 、 Sensory system 、 Spinal cord 、 Extensor muscle 、 CATS 、 Hindlimb 、 Cutaneous stimulation 、 Treadmill 、 Lumbar vertebrae 、 Medicine
摘要: Sensory feedback is a potent modulator of the locomotor pattern generated by spinal networks. The purpose this study was to assess effect cutaneous inputs from back on spinal-generated pattern. cord six adult cats transected at low thoracic levels. Cats were then trained recover hindlimb locomotion. During experiments, skin overlying lumbar vertebrae L2 L7 mechanically stimulated small calibrated clip or manual pinching. Trials without and with stimulation performed treadmill speed 0.4 m/s. Although manually pinching completely stopped locomotion abolished weight support, produced smaller effects. Specifically, more focalized reduced flexor extensor muscle activity led caudal positioning paw contact liftoff. Moreover, greater number steps improper non-plantigrade placements drag stance-to-swing transition. most consistent effects observed mid-lumbar levels, L3-L5. results indicate that modulates excitability circuits involved in generating particularly segments thought be critical for rhythm generation.