Pain relief by wound infiltration with bupivacaine or high-dose ropivacaine after inguinal hernia repair.

摘要: Background and Objectives. Wound infiltration with bupivacaine is often used for pain relief after inguinal hernia surgery. We hypothesized that the lower systemic toxicity of another long-acting local anesthetic similar potency (ropivacaine) would make it possible to increase dose above recommended thereby achieve more effective control. Methods. Elective unilateral open repair was performed on 144 patients at 4 hospitals. Surgery under general anesthesia and, in a double-blind manner, operating field infiltrated 40 mL ropivacaine 7.5 mg/mL (n = 73) or 2.5 71) postoperative relief. Pain rest, mobilization, coughing assessed repeatedly during 24 hours using visual analog scale. The patients' ability walk need supplementary analgesics were also recorded. Results. No statistically significant differences found between two groups respect scores, which reported be less than 15% (median) worst imaginable all examinations consumption analgesics. Those who received could no only minor problems an earlier stage (P < .03). Both treatments well tolerated. Conclusions. anesthetics resulted low scores Bupivacaine 100 mg as 300 mg.