Block copolymer micelles for the encapsulation and delivery of amphotericin B.

作者: Afsaneh Lavasanifar , John Samuel , Saeed Sattari , Glen S. Kwon

DOI: 10.1023/A:1015127225021

关键词: Amphotericin BNuclear chemistryEthylene oxideDrug carrierCopolymerMicelleStearic acidDrug deliveryChemistryOrganic chemistryFatty acid

摘要: Purpose. To assess the effect of fatty acid substitution a micelle-forming poly(ethylene oxide)-block-poly(N-hexyl stearate-L-aspartamide) (PEO-b-PHSA) on encapsulation, hemolytic properties and antifungal activity amphotericin B (AmB).

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