Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart
作者： Detlef Brunkhorst , Heiko v. der Leyen , Wilfried Meyer , Rüdiger Nigbur , Carlos Schmidt-Schumacher
DOI: 10.1007/BF00167264
关键词: Phosphodiesterase 、 Inotrope 、 Internal medicine 、 Pimobendan 、 Endocrinology 、 Chronotropic 、 IBMX 、 Rolipram 、 Milrinone 、 Zaprinast 、 Chemistry
摘要: … III inhibition seems to be a prerequisite for PDE inhibition as a … AR-L 57 Cl provide evidence that a selectivity for PDE III inhibition … Finally, there is no indication that inhibition of PDE I or II …
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