Stress Effects on Tissue Nutrition and Viability

摘要: An early theory of cellular adaptation to altered mechanical force was proposed by Wolff (1892) and states that tissue architecture is strengthened increased activity. emphasized clinical studies pathological specimens. Although Wolff’s Law originally treated adaptations the hip joint, femur vertebrae alterations externally applied loads, it evident this principle more general applies many other tissues as well. For example, joint contractures due immobilization (Akeson et al., 1980) are often prevented passive motion (Frank 1984). Continuous also aids clearance hemarthrosis from synovial fluid (O’Driscoll 1983). Ligaments (Tipton 1975; Amiel 1983, Akeson 1985), tendons Gelberman 1981), bone (Woo 1981) skeletal muscle (Booth Gollnick, 1983) benefit stress in terms healing hypertrophy compared immobilized tissues. However, pointed-out Brickley-Parsons Glimcher (1984), loads may be favorable or unfavorable, depending on specific magnitude depicted Figure 1.1.