Transgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivo.
作者： Zun Liu , Hiroko Segawa , Cumhur Aydin , Monica Reyes , Reinhold G. Erben
DOI: 10.1210/EN.2010-1034
关键词: Kidney 、 G protein 、 Cell culture 、 Phenotype 、 Parathyroid hormone 、 Gs alpha subunit 、 Transgene 、 Internal medicine 、 Biology 、 In vivo 、 Endocrinology
摘要: Targeting XLαs expression to the mouse renal proximal tubule augments Gsα-mediated responses and mitigates PTH-resistance phenotype observed in mice with maternal Gsα ablation.
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endojournals.org参考文章(48)
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