Gastrointestinal Stromal Tumors of Gastric Origin

作者: Chandrajit P. Raut , Jason L. Hornick , Monica M. Bertagnolli

DOI: 10.1007/978-0-387-69182-4_5

关键词: EndoscopyMedicineLaparotomyGastroenterologySunitinib malateBroad spectrumAsymptomaticStromal cellImatinib mesylateInternal medicineMesenchymal stem cell

摘要: Gastrointestinal stromal tumors (GISTs) are rare neoplasms. Although they account for only 0.1%–3% of all gastrointestinal (GI) malignancies (Crosby et al. 2001; DeMatteo 2000; Lewis and Brennan 1996; Nishida Hirota 2000), represent 80% GI mesenchymal (Miettinen Lasota 2001). GISTs may arise from anywhere along the tract exhibit a broad spectrum clinical behavior. Many asymptomatic, discovered incidentally during imaging, endoscopy, or laparotomy unrelated reasons. activity. Some remain stable years, whereas others progress rapidly (DeMatteo Fletcher 2002). Metastases be identified in 15%–50% at time diagnosis (Bauer 2003; Roberts Eisenberg

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