Higher Isolation of NDM-1 Producing Acinetobacter baumannii from the Sewage of the Hospitals in Beijing

摘要: Multidrug resistant microbes present in the environment are a potential public health risk. In this study, we investigate presence of New Delhi metallo-β-lactamase 1 (NDM-1) producing bacteria 99 water samples Beijing City, including river water, treated drinking raw from pools and sewage 4 comprehensive hospitals. For bla NDM-1 positive isolate, antimicrobial susceptibility testing was further analyzed, Pulsed Field Gel Electrophoresis (PFGE) performed to determine genetic relationship among isolates human, as well clinical strains without NDM-1. The results indicate that there higher isolation Acinetobacter baumannii hospitals, while no were recovered obtained river, drinking, or fishpond water. Surprisingly, these markedly different drug resistance pulsed field gel electrophoresis profiles, suggesting evolutionary relationships. Our showed hospital may be one diffusion reservoirs bacteria.