Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer

作者: Daniel K. Nomura , Donald P. Lombardi , Jae Won Chang , Sherry Niessen , Anna M. Ward

DOI: 10.1016/J.CHEMBIOL.2011.05.009

关键词: Cancer researchProstate cancerLipolysisFatty acidEndocrinologyCannabinoid receptorMonoacylglycerol lipaseEndocannabinoid systemCancer cellInternal medicineBiologyLipogenesis

摘要: Cancer cells couple heightened lipogenesis with lipolysis to produce fatty acid networks that support malignancy. Monoacylglycerol lipase (MAGL) plays a principal role in this process …

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