Possible Risk Factors for Candida Esophagitis in Immunocompetent Individuals.

摘要: Background Candida esophagitis (CE) is a condition typically diagnosed in patients who are immunocompromised. Risk factors leading to the development of CE immunocompetent have not been entirely elucidated. This study set out identify risk associated with patients. Methods was single-center retrospective chart review. Patients confirmed by endoscopic biopsy or brushings at our hospital between 2007 and 2017 were reviewed. The medical histories, endoscopy reports pathology results noted. Abdominal pain, heartburn, dysphagia odynophagia common indications for endoscopy. A total 241 identified as having brushing biopsy. Of these patients, 161 excluded due presence immunocompromising 80 included had no underlying conditions. Results Eighty satisfied inclusion criteria. mean age time diagnosis 39.8 years old (95% CI: 34.9 - 44.7). incidences men women similar this (49% 51% men). 56 (70%) 59-80%; P < 0.005) taking proton pump inhibitors (PPIs). Fifteen (19%) previous upper evidence reflux esophagitis, they all treated PPIs subsequently found on repeat 21.6 months PPI treatment. There 16 (20%) without any attributable factor completely healthy. Conclusions an opportunistic infection seen We report incidence In cohort use most CE. could be related hypochlorhydria resulting from use. However, cause remains unclear some