A New Type of Monoterpenoid Indole Alkaloid Precursor from Alstonia rostrata
作者： Xiang-Hai Cai , Mei-Fen Bao , Yu Zhang , Chun-Xia Zeng , Ya-Ping Liu
DOI: 10.1021/OL200996A
关键词: Alstonia rostrata 、 Chemistry 、 Phytochemical 、 Strictosidine 、 Monoterpenoid Indole Alkaloids 、 Tryptophan 、 Secologanin 、 Stereochemistry 、 Indole alkaloid
摘要: Currently, all monoterpenoid indole alkaloids (MIAs) have been derived from strictosidine, which originates the condensation of tryptophan with secologanin in a 1:1 ratio. However, our phytochemical research on Alstonia rostrata revealed potential new precursor for these compounds. We isolated alstrostines A and B, it was determined that they were 1:2 ratio, supported presence type MIA precursor.
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