Distribution of gamma E-forming cells in lymphoid tissues of the human and monkey.

摘要: The sites of synthesis immunoglobulin E were studied by the fluorescent antibody technique. Frozen sections human and monkey tissues treated with guinea pig anti-γE stained against immunoglobuins. results showed that γE-forming plasma cells predominant in respiratory gastrointestinal mucosa regional lymph nodes. In addition to cells, tonsils, adenoids, broncheal mesenteric nodes contained germinal centers anti-γE. contrast, γE scarce spleen subcutaneous A possible role locally synthesized allergy was discussed.