Mitomycin C induces apoptosis in cultured corneal fibroblasts derived from type II granular corneal dystrophy corneas.
作者： Tae Im Kim , Eung Kweon Kim , Young Jae Cho , Seung Il Choi , Hyung Keun Lee
DOI:
关键词: Mitomycin C 、 Extracellular matrix 、 Biology 、 Viability assay 、 Cornea 、 Granular corneal dystrophy 、 Transforming growth factor 、 Transforming growth factor beta 、 Heterozygote advantage 、 Molecular biology
摘要: Purpose The present study investigated the effect of mitomycin C (MMC) on cell viability, apoptosis, and transforming growth factor beta-induced protein (TGFBIp) expression in cultured normal corneal fibroblasts heterozygote or homozygote granular dystrophy type II (GCD II) fibroblasts.
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