Neural Recording Stability of Chronic Electrode Arrays in Freely Behaving Primates

作者: Michael D. Linderman , Vikash Gilja , Gopal Santhanam , Afsheen Afshar , Stephen Ryu

DOI: 10.1109/IEMBS.2006.260814

关键词: NeuroprostheticsAdaptive filterMicroelectrodeNeurophysiologyElectronic engineeringElectrodeElectrophysiologyComputer scienceStability (probability)Spike sorting

摘要: Chronically implanted electrode arrays have enabled a broad range of advances, particularly in the field neural prosthetics. Those successes motivate development prototype implantable prosthetic processors for long duration, continuous use freely behaving subjects. However, traditional experimental protocols provided limited information regarding stability and their recordings. In this paper we present preliminary results derived from duration recordings primate which show variations action potential shape RMS noise across time scales. These suggest that spike sorting algorithms can no longer assume stable signals will need to transition adaptive signal processing methodologies maximize performance.

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