Metabolism in vivo of connective-tissue mucopolysaccharides

作者: E.A Davidson , William Small

DOI: 10.1016/0006-3002(63)91292-7

关键词: Internal medicineGlycosaminoglycanMetabolismHormoneChondroitin sulfateEndocrinologyChondroitinIntervertebral diskConnective tissueChemistryKeratan sulfate

摘要: Abstract The compositon of rabbit nucleus pulposus has been investigated as a function age. ratio keratosulfate to chondroitin sulfate increases uniformly time. Several hormones, notably growth estrogens and androgens are able alter the composition mature tissues towards that represented by younger metabolic activity polysaccharides examined their half-lives estimated. animal appears be extremely inert following synthesis probably half-life in excess 120 days.

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