Canine von Willebrand's disease. A heterogeneous group of bleeding disorders.

摘要: The term "von Willebrand's disease," refers to a group of inherited bleeding disorders, all which are caused by deficiency the multimeric plasma glycoprotein, von Willebrand factor. various forms canine disease can be categorized into one three major types: in type I disease, sizes factor multimers detected plasma; II only smaller found (larger absent); and III is completely absent from or present trace amounts. Von common dogs, but some so mild that they questionable clinical significance.