Pre-processing of microarray data and analysis of differential expression.
作者： Steffen Durinck
DOI: 10.1007/978-1-60327-159-2_4
关键词: Gene 、 Microarray databases 、 DNA microarray 、 Microarray analysis techniques 、 Bioconductor 、 Computer science 、 Expression (computer science) 、 Northern blot 、 Gene expression 、 Computational biology 、 Regulation of gene expression
摘要: Microarrays have become a widely used technology in molecular biology research. One of their main uses is to measure gene expression. Compared older expression measuring assays such as Northern blotting, analyzing data from microarrays inherently more complex due the massive amounts they produce. The analysis microarray requires biologists collaborate with bioinformaticians or learn basics statistics and programming. Many software tools for are available. Currently one most popular freely available Bioconductor. This chapter Bioconductor preprocess data, detect differentially expressed genes, annotate lists interest.
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