Multi-Omic Biogeography of the Gastrointestinal Microbiota of a Pre-Weaned Lamb.
作者： Antonio Palomba , Alessandro Tanca , Cristina Fraumene , Marcello Abbondio , Francesco Fancello
关键词: Microbiota composition 、 Gastrointestinal microbiota 、 Dietary interventions 、 Digestive functions 、 Metaproteomics 、 Zoology 、 Biology
摘要: The digestive functions of the pre-weaned lamb gastrointestinal tracts (GITs) have been subject much research in recent years, but microbial and host underlying these complex processes remain largely unknown. Here, we undertook a proof-of-principle metaproteogenomic investigation on luminal mucosal samples collected from 10 GITs 30-day-old lamb. We demonstrate that analysis diverse ecological niches along can reveal microbiota composition metabolic functions, although low amounts proteins could be identified small intestinal samples. Our data suggest 30-day has already developed mature forestomachs, while effect milky diet appears to more evident remaining GITs. also report distribution relative abundance active at GIT level, with special focus those involved processes. In conclusion, this pilot study supports suitability approach characterization GITs, opening way further studies aimed investigating impact early dietary interventions ruminants.
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