Cerebral Perfusion Does Not Increase after Shunt Surgery for Normal Pressure Hydrocephalus.

摘要: Background and purpose Cerebral blood flow (CBF) has been reported to increase after shunt surgery in patients with idiopathic normal pressure hydrocephalus (iNPH). The aims of this study were investigate if CBF, measured using the noninvasive perfusion MRI method arterial spin labeling (ASL), increased surgery, postoperative change CBF correlated improvement symptoms, baseline data outcome. Methods Twenty-three iNPH prospectively included examined brain clinical tests symptoms at baseline. Eighteen treated implantation reexamined 3 months postoperatively. protocol a pseudo-continuous ASL sequence for imaging. was 12 manually drawn regions interest (ROIs). Results In whole sample, did not shunting any ROI. Preoperative medial frontal cortex an urinary incontinence r = .53, P .022. There no correlations between Conclusions value work-up is uncertain. study, could predict outcome there surgery.