An HPLC method for the pharmacokinetic study of vincristine sulfate-loaded PLGA–PEG nanoparticle formulations after injection to rats

作者: Jianian Chen , Huijuan He , Shaoshun Li , Qi Shen

DOI: 10.1016/J.JCHROMB.2011.05.031

关键词: VincristineEthylene glycolHigh-performance liquid chromatographyChemistryChromatographyMicroparticleSodiumPharmacokineticsExtraction (chemistry)Vincristine SulfateAnalytical chemistryClinical biochemistryCell biologyBiochemistryGeneral Medicine

摘要: … HPLC method for the detection of vincristine in rat plasma after administration of poly(lactic-… Vincristine was extracted from rat plasma and vinblastine sulfate was chosen as the internal …

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