Mucosal Cellular Regeneration and Colorectal Carcinogenesis

作者: N. A. Wright , H. K. Seitz , U. A. Simanowski

DOI: 10.1007/978-3-642-85930-4_15

关键词: Colorectal cancerCell growthCarcinogenesisCell cycleColorectal carcinogenesisCancer researchRegeneration (biology)CancerMedicineCell

摘要: Altered cellular regeneration is the prominent feature that distinguishes cancer from normal tissue. Therefore it of paramount importance to understand cell and its regulation in colonic mucosa during carcinogenesis carcinomas if we want design evaluate new therapeutic measures. Cell proliferation measurement has been domaine histology. However, recent years have seen increasing attempts link molecular biology cycle events proliferation, which will be dealt with elsewhere.

参考文章(91)
Malcolm Alison, Nicholas A. Wright, The biology of epithelial cell populations Clarendon Press , Oxford University Press. ,(1984)
K.M. Pozharisski, V.F. Klimashevski, V.A. Gushchin, Study of kinetics of epithelial cell populations in, normal tissues of the rat's intestines and in carcinogenesis Experimentelle Pathologie. ,vol. 18, pp. 387- 406 ,(1980) , 10.1016/S0014-4908(80)80040-8
P. J. M. Tutton, D. H. Barkla, Cell proliferation in the descending colon of dimethylhydrazine treated rats and in dimethylhydrazine induced adenocarcinomata Virchows Archiv B Cell Pathology. ,vol. 21, pp. 147- 160 ,(1976) , 10.1007/BF02899151
Peter D. M. Macdonald, William W. L. Chang, Ki Mark Mak, Cell population kinetics of 1,2-dimethylhydrazine-induced colonic neoplasms and their adjacent colonic mucosa in the mouse. Virchows Archiv B Cell Pathology Including Molecular Pathology. ,vol. 30, pp. 349- 361 ,(1979) , 10.1007/BF02889113
U. Löhrs, B. Wiebecke, M. Eder, Morphologische und autoradiographische Untersuchung der Darmschleimhautveränderungen nach einmaliger Injektion von 1,2-Dimethylhydrazin Zeitschrift für Die Gesamte Experimentelle Medizin einschließlich experimentelle Chirurgie. ,vol. 151, pp. 297- 307 ,(1969) , 10.1007/BF02052919
A. J. Watson, D. R Appleton, J. P Sunter, Cell proliferation in the gastrointestinal tract Pitman Medical. ,(1980)
Tissue growth factors Springer Berlin Heidelberg. ,(1981) , 10.1007/978-3-642-67986-5
A.I. Bykorez, Yu.D. Ivashchenko, Gastrointestinal Stem Cells and Their Role in Carcinogenesis International Review of Cytology. ,vol. 90, pp. 309- 373 ,(1984) , 10.1016/S0074-7696(08)61493-X
N A Wright, A J Watson, D R Appleton, H S Aldewachi, The effect of starvation and refeeding on cell population kinetics in the rat small bowel mucosa. Journal of Anatomy. ,vol. 119, pp. 105- 121 ,(1975)