Clinically relevant information from sentinel lymph node biopsies of melanoma patients.

作者: Duan-Ren Wen , Alistair J. Cochran , Rong-Rong Huang , Eijun Itakura , Scott Binder

DOI: 10.1002/JSO.21818

关键词: Sentinel lymph nodeRelevant informationImmunohistochemistryStainingPathologyMelanomaRisk categoryMedicine

摘要: Careful laboratory evaluation of sentinel nodes (SNs) is critical to determine the presence tumor. This requires multiple full-face sections from SN, using H&E staining and immunohistochemistry. In future, molecular genetic approaches may be adjunctive microscopy. Number tumor-positive SNs amount location tumor in correlate with spread non-sentinel nodes, subsequent recurrences melanoma death, permitting patient assignment a risk category.

参考文章(55)
Morton Dl, Graham Ls, Sample Wf, Fee Hj, Robinson Ds, Holmes Ec, The determination of lymph shed by colloidal gold scanning in patients with malignant melanoma: a preliminary study. Surgery. ,vol. 84, pp. 626- ,(1978)
J. M. Klaase, M. E. Witte, E. G. Gerrits, W. J. B. Mastboom, L. M. Th. Sterk, Distinguishing nodal naevus from melanoma metastases in the sentinel node in patients with melanoma Nederlands Tijdschrift voor Geneeskunde. ,vol. 150, pp. 1072- 1076 ,(2006)
Alistair J. Cochran, Donald L. Morton, Detection of clinically relevant melanoma metastases requires focused, not exhaustive, evaluation of sentinel lymph nodes. The American Journal of Surgical Pathology. ,vol. 30, pp. 419- 420 ,(2006) , 10.1097/01.PAS.0000178092.61771.C6
Scott R Granter, Phillip H. McKee, J Eduardo Calonje, Pathology of the Skin ,(1996)
Jonathan B. Kruskal, Robert A. Kane, Imaging of primary and metastatic liver tumors. Surgical Oncology Clinics of North America. ,vol. 5, pp. 231- 260 ,(1996) , 10.1016/S1055-3207(18)30379-X
Helene Nortvig Abrahamsen, Stephen J Hamilton‐Dutoit, Jørn Larsen, Torben Steiniche, None, Sentinel lymph nodes in malignant melanoma: extended histopathologic evaluation improves diagnostic precision. Cancer. ,vol. 100, pp. 1683- 1691 ,(2004) , 10.1002/CNCR.20179
Roger F Uren, Robert Howman-Giles, John F Thompson, Helen M Shaw, John M Roberts, Elizabeth Bernard, William H McCarthy, High-resolution ultrasound to diagnose melanoma metastases in patients with clinically palpable lymph nodes. Journal of Medical Imaging and Radiation Oncology. ,vol. 43, pp. 148- 152 ,(1999) , 10.1046/J.1440-1673.1999.00625.X
Charles M. Balch, Seng-Jaw Soong, Jeffrey E. Gershenwald, John F. Thompson, Douglas S. Reintgen, Natale Cascinelli, Marshall Urist, Kelly M. McMasters, Merrick I. Ross, John M. Kirkwood, Michael B. Atkins, John A. Thompson, Daniel G. Coit, David Byrd, Renee Desmond, Yuting Zhang, Ping-Yu Liu, Gary H. Lyman, Aberto Morabito, Prognostic Factors Analysis of 17,600 Melanoma Patients: Validation of the American Joint Committee on Cancer Melanoma Staging System Journal of Clinical Oncology. ,vol. 19, pp. 3622- 3634 ,(2001) , 10.1200/JCO.2001.19.16.3622
Alistair J. Cochran, Bernd-R�diger Balda, Hans Starz, Dieter Bachter, David N. Krag, C. Wayne Cruse, Rik Pijpers, Donald L. Morton, The Augsburg Consensus. Techniques of lymphatic mapping, sentinel lymphadenectomy, and completion lymphadenectomy in cutaneous malignancies. Cancer. ,vol. 89, pp. 236- 241 ,(2000) , 10.1002/1097-0142(20000715)89:2<236::AID-CNCR5>3.0.CO;2-0
Jeffrey D. Wagner, Darrell Davidson, John J. Coleman, Gary Hutchins, Donald Schauwecker, Hee-Myung Park, Robert J. Havlik, Lymph node tumor volumes in patients undergoing sentinel lymph node biopsy for cutaneous melanoma. Annals of Surgical Oncology. ,vol. 6, pp. 398- 404 ,(1999) , 10.1007/S10434-999-0398-4