Shaping Innate Lymphoid Cell Diversity

摘要: Innate lymphoid cells (ILCs) are a key cell type that enriched at mucosal surfaces and within tissues. Our understanding of these is growing rapidly. Paradoxically, play role in maintaining tissue integrity but they also function as drivers allergy inflammation. We present here the most recent how genomics has provided significant insight into ILCs generated enormous heterogeneity canonical subsets. This allowed generation detailed blueprint for to become highly sensitive adaptive sensors environmental changes therefore exquisitely equipped protect immune surfaces.