Endothelial Dysfunction in Children With Obstructive Sleep Apnea Is Associated With Elevated Lipoprotein-Associated Phospholipase A2 Plasma Activity Levels.

作者: Leila Kheirandish‐Gozal , Mona F. Philby , Zhuanghong Qiao , Abdelnaby Khalyfa , David Gozal

DOI: 10.1161/JAHA.116.004923

关键词: Endothelial dysfunctionCholesterolSleep apneaLipoprotein-associated phospholipase A2MedicineObstructive sleep apneaEndocrinologyIncreased riskInternal medicine

摘要: BackgroundObstructive sleep apnea (OSA) is a highly prevalent condition, especially in obese children, and has been associated with increased risk for endothelial dysfunction dislipidemia, whic...

参考文章(57)
Shahar Lavi, Ronit Lavi, Joseph P. McConnell, Lilach O. Lerman, Amir Lerman, Lipoprotein-Associated Phospholipase A2 Review of its Role as a Marker and a Potential Participant in Coronary Endothelial Dysfunction Molecular Diagnosis & Therapy. ,vol. 11, pp. 219- 226 ,(2007) , 10.1007/BF03256243
David Gozal, Leila Kheirandish‐Gozal, Childhood obesity and sleep: relatives, partners, or both?—a critical perspective on the evidence Annals of the New York Academy of Sciences. ,vol. 1264, pp. 135- 141 ,(2012) , 10.1111/J.1749-6632.2012.06723.X
M. H. Park, C. Falconer, R. M. Viner, S. Kinra, The impact of childhood obesity on morbidity and mortality in adulthood: a systematic review. Obesity Reviews. ,vol. 13, pp. 985- 1000 ,(2012) , 10.1111/J.1467-789X.2012.01015.X
Richard B. Berry, Rohit Budhiraja, Daniel J. Gottlieb, David Gozal, Conrad Iber, Vishesh K. Kapur, Carole L. Marcus, Reena Mehra, Sairam Parthasarathy, Stuart F. Quan, Susan Redline, Kingman P. Strohl, Sally L. Davidson Ward, Michelle M. Tangredi, Rules for Scoring Respiratory Events in Sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events Journal of Clinical Sleep Medicine. ,vol. 8, pp. 597- 619 ,(2012) , 10.5664/JCSM.2172
Ram Weiss, Andrew A. Bremer, Robert H. Lustig, What is metabolic syndrome, and why are children getting it? Annals of the New York Academy of Sciences. ,vol. 1281, pp. 123- 140 ,(2013) , 10.1111/NYAS.12030
PT Katzmarzyk, W Shen, A Baxter‐Jones, Jimmy D Bell, NF Butte, EW Demerath, V Gilsanz, MI Goran, V Hirschler, HH Hu, Claudio Maffeis, RM Malina, MJ Müller, Angelo Pietrobelli, JCK Wells, None, Adiposity in children and adolescents: correlates and clinical consequences of fat stored in specific body depots Pediatric Obesity. ,vol. 7, pp. 42- 61 ,(2012) , 10.1111/J.2047-6310.2012.00073.X
Leslie J. Donato, Jeffrey W. Meeusen, Heidi Callanan, Amy K. Saenger, Allan S. Jaffe, Advantages of the lipoprotein-associated phospholipase A2 activity assay. Clinical Biochemistry. ,vol. 49, pp. 172- 175 ,(2016) , 10.1016/J.CLINBIOCHEM.2015.09.002
Parveen K. Garg, Robyn L. McClelland, Nancy S. Jenny, Michael H. Criqui, Philip Greenland, Robert S. Rosenson, David S. Siscovick, Neal Jorgensen, Mary Cushman, Lipoprotein-associated phospholipase A2 and risk of incident cardiovascular disease in a multi-ethnic cohort: The multi ethnic study of atherosclerosis Atherosclerosis. ,vol. 241, pp. 176- 182 ,(2015) , 10.1016/J.ATHEROSCLEROSIS.2015.05.006
Anna Vlahandonis, Gillian M. Nixon, Margot J. Davey, Lisa M. Walter, Rosemary S.C. Horne, Improvement of sleep-disordered breathing in children is associated with a reduction in overnight blood pressure. Sleep Medicine. ,vol. 14, pp. 1295- 1303 ,(2013) , 10.1016/J.SLEEP.2013.07.014
Rakesh Bhattacharjee, Jinkwan Kim, Leila Kheirandish-Gozal, David Gozal, Obesity and obstructive sleep apnea syndrome in children: a tale of inflammatory cascades. Pediatric Pulmonology. ,vol. 46, pp. 313- 323 ,(2011) , 10.1002/PPUL.21370