Temperature modeling and measurement of an electrokinetic separation chip

摘要: This work presents experimental [infrared (IR) thermography] and computational (finite element model) results of temperature distributions an electrokinetic separation chip. Thermal characteristics both the electrolyte solution polymer chip (SU-8) are taken into account in modeling during flow. Multiphysics multiscale simulation couples electrostatics, heat transfer, fluid dynamics. The accompanying IR thermography is a non-contact method, which can measure fractional differences with sub-second time resolution. Any structures or marker molecules interfering experiment not needed. Nominal spot size measurements 30 μm field view several millimeters enabling local chip-scale monitoring simultaneously. As result, we present computer model for chips, enables changes electrophoresis under real operating conditions. accuracy within ±1°C when deviation electrochemical processes account. also suggest that on surface qualitatively reflects inside microchannel average offset 1–2°C.