Sublingual Nucleotides Prolong Run Time to Exhaustion in Young Physically Active Men

摘要: Although dietary nucleotides have been determined to be required for normal immune function, there is limited direct interventional evidence confirming performance-enhancing effects of sublingual in humans. A double-blind, placebo-controlled, randomized trial was conducted evaluate the effect (50 mg/day) administered 14 days thirty young healthy physically active males, on endurance performance and responses. Fasting white blood cell count, natural killer cells (NKC) number, NKC cytotoxic activity, serum immunoglobulin (IgA, IgM, IgG), time exhaustion, peak rate perceived exertion, heart rate, running speed during exercise test were measured at baseline (day 0) post-intervention 14). Time as well significantly higher day (p < 0.05) participants supplemented with compared those who consumed placebo. No significant differences other parameters observed between groups post-intervention. volunteers withdrew before end study nor reported any vexatious side supplementation. The results present suggest that may provide pertinent benefit both an ergogenic immunostimulatory additive males.