Micromechanics of the Lung

作者: Ian A. Greaves , Jacob Hildebrandt , Frederic G. Hoppin

DOI: 10.1002/CPHY.CP030314

关键词: LungInterstitial fluidSurface tensionBiophysicsAnatomyInstabilityMicromechanicsMicroscopyDuct (flow)IsotropyMaterials science

摘要: The sections in this article are: 1 Configuration of Terminal Air Spaces 1.1 Macroscopic Isotropy and Symmetry Expansion 1.2 Alveolus–Alveolar Duct Interactions 1.3 Air-Space Morphometry—Light Microscopy 1.4 Air-Space Morphometry—Electron Microscopy 2 Mechanical Interactions Tissue Surface 2.1 Mechanical Models 2.2 Morphology Presence Absence Surface Tension 2.3 Effects on Capillaries Interstitial Fluid 3 Closure 3.1 Airways 3.2 Alveoli 3.3 Sequence Closure 4 Opening 4.1 Airways 4.2 Alveoli 4.3 Mechanics Opening 4.4 Septal Pleats 5 Gas Trapping 5.1 Foam 5.2 Mechanism 5.3 Trapping Vivo 6 Instability 6.1 Negative Pressure- Volume Compliance 6.2 Configurational Stability 6.3 Surface Tension Elastance 6.4 Positive Elastance 6.5 Network Behavior (Interdependence)

参考文章(56)
G. W. Sybrecht, L. Garrett, N. R. Anthonisen, Effect of chest strapping on regional lung function Journal of Applied Physiology. ,vol. 39, pp. 707- 713 ,(1975) , 10.1152/JAPPL.1975.39.5.707
Ewald R. Weibel, Peter Untersee, Joan Gil, Martin Zulauf, Morphometric estimation of pulmonary diffusion capacity. VI. Effect of varying positive pressure inflation of air spaces. Respiration Physiology. ,vol. 18, pp. 285- 308 ,(1973) , 10.1016/0034-5687(73)90094-7
Jere Mead, TAMOTSU Takishima, DAVID Leith, None, Stress distribution in lungs: a model of pulmonary elasticity. Journal of Applied Physiology. ,vol. 28, pp. 596- 608 ,(1970) , 10.1152/JAPPL.1970.28.5.596
E E Faridy, S Permutt, R L Riley, Effect of ventilation on surface forces in excised dogs' lungs. Journal of Applied Physiology. ,vol. 21, pp. 1453- 1462 ,(1966) , 10.1152/JAPPL.1966.21.5.1453
J. E. Hansen, E. P. Ampaya, Human air space shapes, sizes, areas, and volumes Journal of Applied Physiology. ,vol. 38, pp. 990- 995 ,(1975) , 10.1152/JAPPL.1975.38.6.990
Jere Mead, Mechanical Properties of Lungs Physiological Reviews. ,vol. 41, pp. 281- 330 ,(1961) , 10.1152/PHYSREV.1961.41.2.281
T. A. Wilson, Relations among recoil pressure, surface area, and surface tension in the lung Journal of Applied Physiology. ,vol. 50, pp. 921- 930 ,(1981) , 10.1152/JAPPL.1981.50.5.921
T. G. Klingele, N. C. Staub, Alveolar shape changes with volume in isolated, air-filled lobes of cat lung Journal of Applied Physiology. ,vol. 28, pp. 411- 414 ,(1970) , 10.1152/JAPPL.1970.28.4.411
J. Gil, H. Bachofen, P. Gehr, E. R. Weibel, Alveolar volume-surface area relation in air- and saline-filled lungs fixed by vascular perfusion Journal of Applied Physiology. ,vol. 47, pp. 990- 1001 ,(1979) , 10.1152/JAPPL.1979.47.5.990
E J Burger, P Macklem, Airway closure: demonstration by breathing 100 percent O2 at low lung volumes and by N2 washout. Journal of Applied Physiology. ,vol. 25, pp. 139- 148 ,(1968) , 10.1152/JAPPL.1968.25.2.139