Prehospital serum lactate as a predictor of outcomes in trauma patients: a retrospective observational study.

作者: Francis Guyette , Brian Suffoletto , Jose-Luis Castillo , Jorge Quintero , Clifton Callaway

DOI: 10.1097/TA.0B013E318210F5C9

关键词: Respiratory distressMultiple organ dysfunction syndromeSurgeryOdds ratioRetrospective cohort studyMedicineVital signsInternal medicineTrauma centerResuscitationBlood pressure

摘要: Background: Lactate is associated with morbidity and mortality; however, the value of prehospital lactate (pLA) unknown. Our objective was to determine whether pLA improves identification mortality independent vital signs. Methods: We measured in 1,168 patients transported by rotorcraft a Level I trauma center over 18 months. The primary outcome in-hospital secondary outcomes were emergent surgery multiple organ dysfunction syndrome (MODS). Covariates include age, sex, signs, mental status. created multivariable logistic regression models tested them for interaction terms goodness fit. Cutoff values established reporting operating characteristics using shock (defined as index >0.8, heart rate >110, systolic blood pressure Results: In-hospital 5.6%, 7.4% required 5.7% developed MODS. Median 2.4 mmol/L. (odds ratio [OR], 1.23; p 2 mmol/L added predictive model shock, respiratory distress, or altered sensorium, it improved sensitivity from 88% 97% death, 64% 86% surgery, 94% 99% Conclusion: measurements improve prediction mortality, may who require monitoring, resources, resuscitation.

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