Multiple sclerosis and vitamin B12 metabolism

摘要: Multiple sclerosis (MS) is occasionally associated with vitamin B12 deficiency. Recent studies have shown an increased risk of macrocytosis, low serum and/or CSF levels, raised plasma homocysteine and unsaturated R-binder capacity in MS. The aetiology the deficiency MS often uncertain a disorder binding or transport suspected. nature association unclear but likely to be more than coincidental. There remarkable similarity epidemiology pernicious anaemia. Vitamin should always looked for may aggravate impair recovery. evidence that important myelin synthesis integrity further basic are required.