Scandium triflate-catalyzed selective ring opening and rearrangement reaction of spiro-epoxyoxindole and carbonyl compounds
作者： Hui Jiang , Haohua Jie , Jian Li
DOI: 10.1039/C6RA21264F
关键词: Scandium 、 Ring (chemistry) 、 Medicinal chemistry 、 Yield (chemistry) 、 Rearrangement reaction 、 Oxindole 、 Organic chemistry 、 Trifluoromethanesulfonate 、 Chemistry 、 Catalysis
摘要: Scandium triflate-catalyzed reactions between spiro-epoxyoxindole and carbonyl compounds have been disclosed. The reaction with ketones can be used to synthesize spiro[[1,3]dioxolane-4,3′-indolin] species. Furthermore, an unprecedented rearrangement takes place yield alkylidene oxindole when aromatic aldehydes are as components.
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