Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector.
作者： H. J. Zeh , H. Tahara , M. T. Lotze , U. Gubler , Paul D Robbins
DOI:
关键词: Genetic enhancement 、 Cell culture 、 CD8 、 Interleukin 12 、 Molecular biology 、 Transfection 、 Immune system 、 Biology 、 Paracrine signalling 、 Viral vector
摘要: Our recent studies using IL-12 protein or fibroblasts genetically engineered to secrete IL-12 have demonstrated profound antitumor effects of IL-12 in murine models. The antitumor …
elsevier.com
aai.org参考文章(0)