Andrographolide triggers autophagy-mediated inflammation inhibition and attenuates chronic unpredictable mild stress (CUMS)-induced depressive-like behavior in mice.

作者: Ji Geng , Jia Liu , Xiao Yuan , Wen Liu , Wenjie Guo

DOI: 10.1016/J.TAAP.2019.114688

关键词: InflammationTail suspension testBehavioural despair testInflammasomeAndrographolidePharmacologyAutophagyDownregulation and upregulationPrefrontal cortexChemistry

摘要: … In order to evaluate andrographolide mediated autophagy in CUMS mice, … , CUMS group, CUMS treated with 5 mg/kg andrographolide group, CUMS treated with CQ group and CUMS …

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