A role of aryl hydrocarbon receptor in the antiandrogenic effects of polycyclic aromatic hydrocarbons in LNCaP human prostate carcinoma cells.
作者： Ryoichi Kizu , Kazumasa Okamura , Akira Toriba , Hiroshi Kakishima , Atsushi Mizokami
DOI: 10.1007/S00204-003-0454-Y
关键词: Aryl hydrocarbon receptor 、 Fluoranthene 、 Endocrinology 、 LNCaP 、 Chrysene 、 Pyrene 、 Androgen receptor 、 Mechanism of action 、 Endocrine disruptor 、 Chemistry 、 Molecular biology 、 Internal medicine
摘要: … Binding affinities of the five polycyclic aromatic hydrocarbons (PAHs) for human androgen receptor (AR). DMSO and 250 nM milbolerone solutions were used as a blank (inhibition 0%) …
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