Inflammatory neuroprithy in homosexual men with lymphadenopathy

作者: W. I. Lipkin , G. Parry , D. Kiprov , D. Abrams

DOI: 10.1212/WNL.35.10.1479

关键词: Segmental demyelinationCranial nerve dysfunctionPathologyMedicineVasculitisSensory symptomsSural nerveAxonal degenerationPeripheral neuropathyWeakness

摘要: Twelve homosexual men had peripheral neuropathy with fever, night sweats, and lymphadenopathy. Sensory symptoms predominated, but there was also weakness cranial nerve dysfunction. Manifestations were multifocal in nine distal symmetric three. CSF abnormal all eight patients examined. Sural five showed axonal degeneration, accompanied two by segmental demyelination. Four epineurial endoneurial perivascular chronic inflammatory cells without evidence of vasculitis. Neuropathy remitted spontaneously six patients. received steroids clinical response, although one later responded to plasmapheresis-lymphocytapheresis. progressed AIDS.

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