NMDA receptor blockers in the therapy of urogenital disease
作者： Nestor F. Gonzalez-Cadavid , Jacob A. Rajfer
DOI:
关键词: Disease 、 Genitourinary system 、 Ketamine 、 Dextromethorphan 、 NMDA receptor 、 Amantidine 、 Receptor 、 Medicine 、 Hyperplasia 、 Pharmacology
摘要: Methods are presented for the treatment of benign prostatic hyperplasia. The methods provide administration to a person at least one compound identified generically as antagonists N-methyl-D-aspartate receptors. These compounds selected from group consisting memantidine, amantidine, dextromethorphan and ketamine.
lens.org 参考文章(60)
J Kornhuber, M Weller, K Schoppmeyer, P Riederer, Amantadine and memantine are NMDA receptor antagonists with neuroprotective properties. Journal of Neural Transmission-supplement. ,vol. 43, pp. 91- 104 ,(1994)
Néstor F. González‐Cadavid, Tripathi Rajavashisth, Jacob Rajfer, Dolores Vernet, Yining Xie, Alida Hung, José Antonio Rodríguez, Expression of Inducible Nitric Oxide Synthase in Smooth Muscle Cells From Rat Penile Corpora Cavernosa Journal of Andrology. ,vol. 16, pp. 469- 481 ,(1995) , 10.1002/J.1939-4640.1995.TB00567.X
T. Ishii, K. Moriyoshi, H. Sugihara, K. Sakurada, H. Kadotani, M. Yokoi, C. Akazawa, R. Shigemoto, N. Mizuno, M. Masu, Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. Journal of Biological Chemistry. ,vol. 268, pp. 2836- 2843 ,(1993) , 10.1016/S0021-9258(18)53849-7
Stephen R. Saklad, Sheri A. Thornberg, A review of NMDA receptors and the phencyclidine model of schizophrenia Pharmacotherapy. ,vol. 16, pp. 82- 93 ,(1996) , 10.1002/J.1875-9114.1996.TB02920.X
S.I. Said, H.I. Berisha, H. Pakbaz, N-methyl-d-aspartate receptors outside the central nervous system: Activation causes acute lung injury that is mediated by nitric oxide synthesis and prevented by vasoactive intestinal peptide Neuroscience. ,vol. 65, pp. 943- 946 ,(1995) , 10.1016/0306-4522(95)00021-A
D Vernet, L Cai, H Garban, M L Babbitt, F T Murray, J Rajfer, N F Gonzalez-Cadavid, Reduction of penile nitric oxide synthase in diabetic BB/WORdp (type I) and BBZ/WORdp (type II) rats with erectile dysfunction. Endocrinology. ,vol. 136, pp. 5709- 5717 ,(1995) , 10.1210/ENDO.136.12.7588327
David F. Penson, Chris Ng, Liping Cai, Jacob Rajfer, Nestor F. González-Cadavid, Androgen and Pituitary Control of Penile Nitric Oxide Synthase and Erectile Function in the Rat Biology of Reproduction. ,vol. 55, pp. 567- 574 ,(1996) , 10.1095/BIOLREPROD55.3.567
Yining Xie, Hermes Garban, Chris Ng, Jacob Rajfer, Nestor F. Gonzalez-Cadavid, Effect of Long-term Passive Smoking on Erectile Function and Penile Nitric Oxide Synthase in the Rat The Journal of Urology. ,vol. 157, pp. 1121- 1126 ,(1997) , 10.1016/S0022-5347(01)65153-X
Denise Wietlispach Claussen, Levsin (hyoscyamine sulfate USP). Gastroenterology Nursing. ,vol. 17, pp. 37- 38 ,(1994) , 10.1097/00001610-199408000-00011
Andreas Wenzel, Louis Scheurer, Ralf Künzi, Jean Marc Fritschy, Hanns Mohler, Dietmar Benke, Distribution of NMDA receptor subunit proteins NR2A, 2B, 2C and 2D in rat brain. Neuroreport. ,vol. 7, pp. 45- 48 ,(1995) , 10.1097/00001756-199512000-00010